The full text of this article is available in pdf format. Magnetic resonance spectroscopy and its clinical applications. A large body of published work shows that proton hydrogen 1 1 h magnetic resonance mr spectroscopy has evolved from a research tool into a clinical neuroimaging modality. Manual on contrast media, and the acr guidance document on mr safe. Magnetic resonance spectroscopy mrs is a proven and useful method for the. The clinical usefulness of 1h mr spectroscopy has been established for brain neoplasms, neonatal and pe diatric disorders hypoxiaischemia. Introduction to clinical in vivo mr spectroscopy request pdf. Pdf guidelines for using proton mr spectroscopy in.
Herein, the authors present a summary of brain disorders in which mr spectroscopy has an impact on patient management, together with a critical consideration of common data acquisition and processing procedures. Clinical proton mr spectroscopy in central nervous system. Brain neoplasms, mri, mrspectroscopy, echotime, pitfalls. In vivo nmr spectroscopy is known as magnetic resonance spectros copy mrs. Techniques and applications is an excellent, wellorganized textbook introducing the reader to principles, physics, and practical clinical applications of mr spectroscopy mrs. Clinical proton mr spectroscopy in central nervous. Guidelines for using proton mr spectroscopy in multicenter clinical ms studies. Josephs hospital and medical center, phoenix, arizona. Clinical proton mr spectroscopy in central nervous system disorders.
Techniques and applications in vivo magnetic resonance spectrosopy mrs is increasingly being used in the clinical setting, particularly for neurological. Baseline errors can be corrected using automated or manual software so that all spectra have a. Magnetic resonance spectroscopy is a highly sensitive technique in addition to conventional magnetic resonance imaging in characterising and differentiating between neoplastic and nonneoplastic. The article documents the impact of 1h mr spectroscopy in the clinical evaluation of disorders of the central nervous system. Clinical applications of proton mr spectroscopy ajnr. Magnetic resonance spectroscopy mrs provides useful information regarding metabolic composition in the tissues, and advanced spectroscopic methods are.
The article documents the impact of 1h mr spectroscopy in the clinical evaluation of disorders of the central. Pdf clinical applications of proton mr spectroscopy. This 1959 prediction has become a reality in 1995, when examinations using mr spectroscopy and mr imaging are allowing physicians direct routine clinical diagnoses that were previously unobtainable by other radiologic or clinical tests. Current clinical applications of mr spectroscopy of the brain. Mrs has been applied as both a research and a clinical tool in order to detect. Basic principles and clinical applications of magnetic resonance. Basic principles and clinical applications of magnetic resonance spectroscopy in neuroradiology stephan ulmer, md, martin backens, phd, and frank j. Magnetic resonance mr spectroscopy has received little attention from the clinical radiol ogy community. Division of neuroradiology, barrow neurological institute, st. Magnetic resonance spectroscopy mrs provides a noninvasive. Clinical pitfalls related to short and long echo times in cerebral mr.
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